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PURPOSE: The purpose of this study was to investigate the topical off label use of bimatoprost, travoprost, and latanoprost for enhancement of eye lash growth.

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Localization of discrete regions in human Nur77 promoters that respond to PGF 2 and Butaprost treatment provides a clue for further studies on the mechanisms of PGF 2 - and Butaprost-induced upregulation of Nur77 gene expression at the transcriptional level.

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Follicles treated with bimatoprost grew a third more hair than untreated samples in just nine days.

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