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Since the P values obtained with this test were statistically significant, we also compared any treatment with no treatment, treatments including allopurinol with treatments without allopurinol, and meglumine antimoniate with both allopurinol and the combination of allopurinol plus meglumine antimoniate.

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One of the myths that I wrote about in my post is: “Once a gout attacks starts, there is nothing you can do but ride it out”.

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The dosage of antihypertensive drugs, lipid-lowering agents, and antiplatelet drugs were continued and adjusted according to the individual patient's clinical condition.

Assess for infection (vital signs; appearance of wound, sputum, urine, and stool; WBC) at beginning of and throughout therapy.

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The side effects for me included profuse gas, belching, ringing in the ears, (seldom) increase in heartburn (severe)had a little bit of skin peeling at onset.

KSA was a Takeda employee at the time work was performed, who helped with development of the study protocol, reviewed and interpreted data analyses, and made revisions to the manuscript.

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Surgical removal of dead tissue may be necessary in very severe reactions.

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Arhalofenate, an investigational uricosuric drug that also prevents the local release of inflammatory cytokines involved in gout attacks, was effective in preventing disease flares in this most common inflammatory arthritis.

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