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What causes a pituitary tumor to grow? Tumors can be caused by DNA changes that turn on oncogenes or turn off tumor suppressor genes. Some people inherit gene mutations (changes) from their parents that greatly increase their risk for developing pituitary tumors. Many growth hormone-secreting adenomas have an acquired mutation in a gene called GNAS1.
CAN problems with pituitary gland cause weight gain? When the cause is too much ACTH production from the pituitary it's called Cushing's disease. In adults, the symptoms can include: Unexplained weight gain (mostly in the face, chest, and belly)
How do antipsychotics cause hyperprolactinemia? Hyperprolactinaemia With Antipsychotics. Dopamine acts on the pituitary as an inhibitor of prolactin secretion. Blockade of dopamine D2 receptors by typical antipsychotics and risperidone can cause hyperprolactinaemia in males and females. Resulting hypogonadism may cause osteoporosis.
What triggers prolactin? One of the main regulators of the production of prolactin from the pituitary gland is the hormone called dopamine, which is produced by the hypothalamus, the part of the brain directly above the pituitary gland. Dopamine restrains prolactin production, so the more dopamine there is, the less prolactin is released.
Can a pituitary tumor cause fatigue? Fatigue is extreme exhaustion or tiredness. It is the most common problem that people with a pituitary tumor experience. A pituitary gland tumor may cause fatigue if it lowers levels of cortisol, thyroid hormone, or growth hormone.
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