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What is the best medicine for gout? Treatment Nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs include over-the-counter options such as ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve), as well as more-powerful prescription NSAIDs such as indomethacin (Indocin) or celecoxib (Celebrex). Colchicine. Corticosteroids.
Where does gout hurt? The symptoms of gout are due to the formation of uric acid crystals in the joints and the body's response to them. Gout most classically affects the joint in the base of the big toe. Gout attacks often occur without warning in the middle of the night. Most gout cases are treated with specific medications.
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