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What kind of medicine is Triamterene HCTZ? Triamterene / hydrochlorothiazide is an oral diuretic (water pill) that is used for treating high blood pressure (hypertension) and edema (water accumulation). It is a combination of two different diuretics. The FDA approved triamterene / hydrochlorothiazide in December 1965.
What is the difference between chlorothiazide and hydrochlorothiazide? HCTZ has one additional hydrogen substituted on a nitrogen on the sulfonamide ring compared with chlorothiazide. All thiazides have a similar dual-ring structure. Though commonly considered a thiazide, chlorthalidone is not a benzothiadiazine and is more appropriately called a thiazide-like diuretic.
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