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I am starting my 3rd year on Femara for breast cancer treatment and I have had wonderful results. This medication helped me get considerable control over my tumors which stabilized since I started taking Femara. I have had no side effects at all what is very much uncommon for cancer medications, I think. I am now over 56 and am still very active and otherwise healthy. I believe that if I were depressed and negative there would be no positive result from the treatment. Now I am looking forward to many more years of good health with Femara.
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I have been on Femara for almost 5 years now. My oncologist says that Femara is the reason of my improvements. My tumors naturally stopped growing since I started taking this medication. And the only side effect that I have noticed was light migraine after taking the drug, but it is almost unnoticeable. Three of my friends (whom I met at the hospital when I was just starting visiting my oncologist regularly) also started taking Femara simultaneously with me. They report improvement in this or that degree, but still they are happy with the way Femara works. Some of them had noticed hair thinning during treatment, but sometimes you just have to choose.

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Femara (letrozole) for Breast Cancer: "stage I breast cancer.

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No dosage adjustment is recommended for patients with mild to moderate hepatic impairment, although Femara blood concentrations were modestly increased in subjects with moderate hepatic impairment due to cirrhosis.

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There is no clinically significant increased risk of birth defects or miscarriage for women on these drugs unless they have polycystic ovary syndrome, and then their risk for miscarriage may increase.

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Leupron injections to stop ovarian function, and so will now switch from Tamoxifen to Femara for hormone therapy.

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Median treatment duration was 24 months, and median follow-up duration was 26 months, 76% of the patients have been followed for more than 2 years, and 16% of patients for 5 years or longer.

Since i don't know any other information- such as the staging- the goal of therapy, your tolerance etc, i would suggest you to discuss this matter with your oncologist.

I'm reading about the side effects and as many as 50% of women has the same pain as I do.

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The possibility that SSRIs might, by inhibiting CYP2D6, slow the metabolism of tamoxifen and reduce its potency is a concern given that as many as one-fourth of breast cancer patients experience clinical depression and may be treated with SSRIs.

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BIG 1-98 trial found that the aromatase inhibitor Femara (chemical name: letrozole) improved both disease-free survival (living without the cancer growing) and overall survival (living whether or not the cancer grew) compared to tamoxifen in postmenopausal women diagnosed with estrogen-receptor-positive, HER2-negative breast cancer.

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Joe; I am a runner so cutting that out was not easy for me, but they do allow you and in fact insist that you walk so I power walked 3 miles each day until I had lost the first 30 pounds then I started running again and lost 25 more pounds.

All patients were administered 5 days of a fixed dose of letrozole beginning day 3 of their cycle; if the patient was anovulatory, medroxyprogesterone was administered to induce menses.

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During the 2 year period, fractures were reported by 4 of 103 patients (4%) in the Letrozole arm, and 6 of 97 patients (6%) in the tamoxifen arm.

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In patients whose cancer expresses an over-abundance of the protein, a known as (Herceptin) is used to block the activity of the HER2 protein in breast cancer cells, slowing their growth.

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