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HADS, hospital anxiety and depression scale; ICOAP, intermittent and constant osteoarthritis pain scale; MRI, magnetic resonance imaging; MTX, methotrexate; NHS, National Health Service; NRS, numerical rating scale; OA QoL, osteoarthritis quality of life; PIS, patient information sheet; SF-12, Short Form-12; WOMAC, Western Ontario and McMaster Osteoarthritis Index.
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