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GIST is a rare tumor that begins in the gastrointestinal tract, such as the stomach or small bowel.

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Pinkel D: Differentiating juvenile myelomonocytic leukemia from infectious disease.

The only differences between generics and their brand-name counterparts is the generics are less expensive and may look slightly different (e.

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In a study of the long-term effects of the drug, survival of patients with a complete cytogenetic remission was not significantly different from the general population, according to Carlo Gambacorti-Passerini, MD, of the University of Milano Bicocca in Monza, Italy, and colleagues.

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As recommended by the Independent Data Monitoring Committee, the study was terminated prematurely prior to the pre-specified interim analysis.

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You should tell your healthcare professional if you have or had any unusual allergic reaction to Gleevec; if you are allergic to any other substances (foods, preservatives, or dyes); are or may be pregnant, are planning to become pregnant, or are breast-feeding; have anemia, platelet problems, or white blood cell problems; have chickenpox (including recent exposure) or herpes zoster (shingles); have liver disease; have an infection; or if you or anyone to whom you might be exposed has recently had or plans to have any immunizations (vaccinations).

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For some, bone marrow transplant from a matched sibling donor or a matched, unrelated donor may be favored when remission is obtained.

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The IPAB on 26 June 2009 modified the decision of the Assistant Controller of Patents and Designs stating that ingredients for grant of patent novelty and non obviousness to person skilled in the art were present in the application but rejected the application on the ground that the drug is not a new substance but an amended version of a known compound and that Novartis was unable to show any significant increase in the efficacy of the drug and it, therefore, failed the test laid down by section 3(d) of the Indian Patents Act.

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Dasatinib (Sprycel): Indicated for the treatment of adult patients with chronic myeloid leukemia in chronic, accelerated, or myeloid or lymphoid blast phase who are resistant or intolerant to prior therapy including imatinib.

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