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Octreotide Lar resolves severe chemotherapy-induced diarrhoea (CID) and allows continuation of full-dose therapy.

The risk of side effects that affect the kidneys may be increased.

SGN-CD33A: Preclinical and phase 1 interim clinical trial results of a CD33-directed PBD dimer antibody-drug conjugate for the treatment of acute myeloid leukemia (AML).

Capecitabine doses were reduced by 25% for any grade 3 or 4 hematological toxicity, except anemia.

Despite the absence of objective standards, scientific validation, and adequate statistical studies, a natural question to ask is how well fingerprint examiners actually perform.

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After 2003, patients enrolled in NSABP B-31 could also receive weekly paclitaxel at the investigator's discretion.

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Xeloda (capecitabine) is an oral chemotherapy drug approve by the FDA to treat metastatic breast cancer in people who have not responded to medications like Taxol (paclitaxel), Taxotere or Adrimycin or anthracycline-containing chemotherapy options.

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Now that you can find how a gene mutation can change a patient's response to a drug and why pharmacogenomics are important for testing new drugs, repeat the procedure above for additional alleles or other drugs, such as carbamazepine, mercaptopurine, warfarin, or others listed in Table 1 above.

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Patients with chemotherapy-naive HER2-positive advanced gastric cancer were eligible.

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The 20-year risk of cancer death was also lower in the aspirin group for all solid cancers.

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The quality-of-life component of this trial was published separately and minimal short-term quality-of-life benefits with LAC were reported.

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At our institution, monitoring of these patients includes weekly blood counts and weekly assessment of diarrhea and hand-foot syndrome.

Oxaliplatin and irinotecan were applied in 29 and 35 patients (35% and 43%), respectively, with only 17 patients (21%) receiving both drugs consecutively.

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Safety data (excluding the primary safety end point) were reported comprehensively 19 months after the last patient was enrolled.

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CREATE-X is a multicenter open-label randomized phase III trial evaluating this major clinical issue using capecitabine (X) in pts without pCR after NAC (UMIN000000843).

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Saif MW, Eloubeidi MA, Russo S, Steg A, Thornton J, Fiveash J, Carpenter M, Blanquicett C, Diasio RB, Johnson MR: Phase I study of capecitabine with concomitant radiotherapy for patients with locally advanced pancreatic cancer: expression analysis of genes related to outcome.

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