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Does long term use of effexor cause weight gain? A: Weight gain was reported as an infrequent side effect by about 1 percent of patients taking Effexor XR. It was more common to see weight loss in patients taking this medication.
How long does it take for venlafaxine to kick in? Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
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