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Fourteen participants with schizophrenia and 16 healthy participants passively hear sounds while watching a silent nature video.

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In this sense, we can say that humans are hard wired for anxiety, and because of this wiring we can never entirely eliminate it.

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After 1 year, the patients in the group receiving the extra interventions were more compliant with their medications, had fewer rehospitalizations, and experienced better quality of life.

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With respect to neurological side effects, there was no significant difference between groups in extrapyramidal symptom scales.

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One meta-analysis suggested that the addition of antidepressants to antipsychotics might help treat the negative symptoms of chronic schizophrenia, which can be difficult to distinguish from depression.

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Patients were rated on clinical symptoms on PANSS and a five-factor model was used to subdivide the items.

The authors also noted that the clinical meaning of these many findings, many of them quite modest, remains unclear.

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Atypical antipsychotics are standard drugs for schizophrenia.

Background: Cannabis is a widely used recreational drug which increases the risk of psychosis.

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Risperidone safety and efficacy in the treatment of bipolar and schizoaffective disorders: results from a 6-month, multicenter, open study.

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The goal of this study is to determine the effectiveness of the various programs within the Kennedy Krieger Family Center (KKFC) using data from a computerized clinical database.

First-degree biological relatives of individuals with this disorder have an increased risk of also having this disorder.

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We evaluated the association of PE (measured by the CBCL-psychosis subscale) with the presence of any psychiatric diagnoses using a logistic regression model.

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These analyses are aimed at (a) assessing the potential causal relationship to schizophrenia, directionality of effect, cellular context, and potential safety liability, and (b) identifying a putative hypothesis for therapeutic intervention.

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Data was collected at a 2010 Welcome Home event, and chart reviews of VA treatment utilization were completed one year later.

Practice parameter for the assessment and treatment of children and adolescents with schizophrenia.

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Post-hoc, atrophy of subfields in the right hemisphere of both schizophrenia and bipolar groups broadly correlated with illness severity: significant correlations included GCL, CA1, CA3 and ML with negative symptom severity, and subiculum with declining psychosocial functioning.

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Head-to-head comparisons with antipsychotic drugs (usually chlorpromazine) have generally found lithium to be superior in terms of overall improvement in symptoms, mood, and ideation, but worse with respect to motor hyperactivity and onset of action.

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Such an approach has been found to be problematic in the case of ziprasidone hydrochloride since, once a viscosity agent has been added, when the ziprasidone hydrochloride eventually settles, it tends to form a thin cake which sits on the bottom and can be very difficult to break up and to re-suspend.

These findings need to be tested further but could have implications for the treatment and management of violence risk in patients with schizophrenia.

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Conclusion: External-personal attribution style and hostile attribution under ambiguous situations contribute to paranoid delusions, worse performance on recognition of neutral faces is related to paranoid delusions but to a lesser degree, while ToM deficit is more related to disorganized symptoms.

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In 2004, the FDA extended its approval to include Geodon as a in the treatment of acute or episodes in bipolar I disorder, with or without psychotic features.

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Less is known however about the neural systems associated with metacognition in this population.

Predictors of antipsychotic treatment response in patients with first-episode schizophrenia, schizoaffective and schizophreniform disorders.

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In the second phase of the study, the effect of ziprasidone on QTc length was not augmented by the presence of a metabolic inhibitor (ketoconazole 200 mg BID).

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Ziprasidone Psychiatry A neuropharmacologic used for schizophrenia and to prevent psychotic relapses.

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If a person participates in psychosocial rehabilitation, she is more likely to continue taking their medication and less likely to relapse.

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Other effectiveness parameters assessed at baseline (immediately before ziprasidone for trials started at Stanford, or at first visit taking ziprasidone in trials started before Stanford) and at last visit taking ziprasidone included: (1) clinical status (percentage of patients with euthymia vs syndromal or subsyndromal depression vs syndromal or subsyndromal mood elevation); (2) Clinical Global Impression-Severity of Illness (CGI-S) scores; (3) Global Assessment of Functioning (GAF) scores; and (4) weight.

Conclusion: Proteomic findings support the dysfunction in energy metabolism, more specifically on glycolysis.

This study assessed working memory performance and gamma oscillatory activity, which is known to be aberrant in patients with SZ, in both smoker and non-smoker patients with SZ compared to smoker and non-smoker healthy subjects.

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Prophylactic use of anticholinergic medication for extrapyramidal symptoms was prohibited.

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Background: Semantic fluency is widely used and has shown to be useful in detecting cognitive deficits across a wide range of disorders as multiple cognitive processes are implicated in fluency performance.

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Antiseizure medications used for bipolar disorder treatment include valproic acid (Depakene, generic), divalproex sodium (Depakote, generic), and lamotrigine (Lamictal, generic).

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While these medications provide modest PD symptom relief, they can be used as first-line therapy or add-on therapy to levodopa.

With respect to the noted metabolic side effects of SGA treatment, the long term health consequences of obesity and dyslipidemia in children are concerning.

The administration of anti-craving agents (naltrexone) led to a decrease of drug intake.

TdP or QTc interval prolongation to proarrhythmic levels) to be detected is of the order of 1 in 1000 and the incidence of the same event to be detected, when drug-induced, is 1 in 1000, the number of patients required in the safety database would have to approach approximately 20000.

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Subjects were required to discontinue any antipsychotic medications within the 4 wk immediately preceding the baseline visit, any antidepressant within 3 wk of screening or any fluoxetine, specifically, within 5 wk of screening.

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The effect of increased nAChR desensitization induced by smoking affects the degree of synergism.

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Ziprasidone should be used in pregnant women only if the potential benefits outweigh the potential risks.

We used RNA Sequencing assessing expression in hippocampus, prefrontal cortex, and striatum.

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These findings provide a foundation from which heritable factors contributing to community functioning in schizophrenia can be differentiated from those contributing to functioning in psychiatric disorders in general, which may inform the development of environmental interventions.

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