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For patients randomized to Aranesp, the initial weekly dose was determined on the basis of the previous total weekly dose of recombinant erythropoietin.
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We are providing this information solely as a courtesy and, as such, it is in no way a recommendation as to the safety, efficacy or appropriateness of any particular drug, regimen, dosing schedule for any particular cancer, condition or patient nor is it in any way to be considered medical advice.
However, as children get older than 18-months of age, their total blood volumes are larger and the benefits of Procrit seem become less; therefore, we typically do not recommend giving this drug to older todlers.
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In the pooled analysis, efficacy was demonstrated by a reduction in the proportion of patients who received an RBC transfusion from week 5 through end of the study in the subset of patients who were remaining on therapy for 6 or more weeks.
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In a postmarketing prospective study of 447 patients with chronic renal failure treated with epoetin and followed at 68 centers, average hematocrit levels increased from 25.
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