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How does warfarin inhibit vitamin K? Warfarin inhibits epoxide reductase (specifically the VKORC1 subunit), thereby diminishing available vitamin K and vitamin K hydroquinone in the tissues, which inhibits the carboxylation activity of the glutamyl carboxylase. The end result of warfarin use, therefore, is to diminish blood clotting in the patient.
How do I keep my INR stable? Here are some tips on how you can help keep your INR number as stable as possible: Take your Warfarin exactly as prescribed. Take your Warfarin dose at the same time every day. Never double a dose for a missed dose. Keep all scheduled visits or call promptly to reschedule.
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