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Although both sensitivity and specificity of this test is limited, most patients who react to their own serum to produce a wheal and flare reaction upon intradermal skin test, are responding to an IgG immunoglobulin with a positive incidence of about 30%.
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Although EVR TDM frequency is less than with CNIs because of the lower intrapatient variability with EVR, the analytical turnaround time should ideally be the same as that of the associated CNI (except in cases of suspected DDI or if EVR is a major component of the immunosuppressive regimen when it should be the same).
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