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FTC was not genotoxic in the reverse mutation bacterial test (Ames test), mouse lymphoma or mouse micronucleus assays.
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This could be due to the small number of HIV-positive women in this subgroup or to low adherence to the gel, leading to similarly high incidence rates of HSV-2 infection among HIV-infected women assigned to tenofovir gel and those assigned to placebo gel.
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If discontinuation of therapy for chronic hepatitis B results in hepatic flare, therapy for chronic hepatitis B should be reinstituted ( BIII).
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Insufficient evidence to determine whether reinitiation of therapy alters the course of posttreatment exacerbations of hepatitis.
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The smaller the net benefit and the lower certainty for that benefit, the more likely weak recommendation warranted.
However, aqueous penicillin G is preferred because of its higher penetration into the CSF.
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HIV cure may be possible. News of such a cure started to bubble forth during the summer of 2012, when there were two separate lines of research that demonstrated that HIV could be brought under control in certain groups of patients.
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Polymerase chain reaction diagnosis of primary human herpesvirus-6 infection in the acute care setting.
New soluble-formazan assay for HIV-1 cytopathic effects: application to high-flux screening of synthetic and natural products for AIDS-antiviral activity.
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only 25 percent of men and women who had used the tenofovir gel said they liked it
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Indication: This drug is indicated for HIV patients.
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Your doctor may want to check your liver function for several months after you stop using Viread.
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VIREAD may affect the way other medicines work, and other medicines may affect how VIREAD works.
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Side effects may include fever, rash, fatigue, vomiting, diarrhea, abdominal pain, malaise or fatigue, loss of appetite and respiratory symptoms.
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Methodologies to diagnose and monitor dry eye disease: report of the Diagnostic Methodology Subcommittee of the International Dry Eye Workshop.
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Researchers found that people with rare mutations that switch off a single copy of a gene called NPC1L1 are protected against high levels of bad LDL cholesterol and narrowing of the hearts arteries.
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But it appears the Daraprim alternative compound was not born out of a physical inability to use Daraprim, but a financial one.
A generic drug is not worse than brand medicine.
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Some of this kidney dysfunction will be related to tenofovir toxicity, and some will not.
ARF in HIV-infected patients in ambulatory care settings is most frequently due to pre-renal azotemia or acute tubular necrosis, possibly caused by exposure to nephrotoxic agents.
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Plasma concentrations and effects potentially increased or decreased by efavirenz.
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One study found rtA194T (alanine to threonine substitution at codon 194) in conjunction with lamivudine-resistant mutations in 2 of 43 (5%) HIV-HBV coinfected patients who had persistently detectable HBV DNA levels despite 24 weeks of combination therapy of tenofovir and lamivudine.
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All reported P values were two-sided and have not been adjusted for multiple testing.
Characterization of Peripheral and Mucosal Immune Responses In Rhesus Macaques on Long-Term Tenofovir and Emtricitabine Combination Antiretroviral Therapy.
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Videx, Videx EC (didanosine); tenofovir DF (a component of ATRIPLA) may increase the amount of didanosine in your blood, which could result in more side effects.
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Because the HIV-related clinical entities associated with HHV-8, such as KS and Castleman's disease, are oncologic and traditionally have been treated with cytotoxic chemotherapy, specific treatment is not included in this report.
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Doctors routinely use eGFR because assessing the actual GFR (written as aGFR) would be cumbersome for patients.
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The agents listed in are all not recommended for use in PEP regimens and are not likely to be used; however, clinicians should be aware that these agents should not be prescribed in pregnant women.
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He travelled across the globe collecting blood samples, investigating the interplay between disease, environment, and genetics with the goal of designing targeted interventions for at-risk individuals that could prevent them from getting sick.
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Immune reconstitution syndrome has been reported in patients treated with combination antiretroviral therapy, including TRUVADA.
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EMTRIVA is the brand name for emtricitabine, a synthetic nucleoside analog of cytidine.
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Resistance: In vitro, HIV-1 isolates with reduced susceptibility to tenofovir alafenamide have been selected, including virus with the K65R substitution (sometimes with S68N or L429I substitutions) and virus with the K70E substitution.
If there is significant risk without benefit, it would be appropriate to discourage the treatment.
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