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Are SSRIs or SNRIs better for anxiety? SNRIs increase levels of both serotonin and norepinephrine. As with SSRIs, it is the longer-term effects of SNRIs that are helpful with anxiety. The immediate effect of SNRIs, like SSRIs, is sometimes to increase anxiety, so they, too, may need to be started gradually. Anxiety reduction occurs after a week or 10 days.
How long does severe depression last? How long does depression last ? On average, an episode of major depression lasts 4 to 8 months, although this duration can be shortened by treatment. Most people recover within 3 to 6 months with treatment, although it can take longer than this for some.