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I was on Tamoxifen for 2 years following breast cancer and doing fine. My oncologist wanted to try Femara because it could be a little better. I was on it for about 3 months when I awoke in the middle of the night with horrible joint pain, It had been coming on slowly, but I thought it was carpel tunnel, maybe arthritis. Then I realized that my doctor had said that joint pain was a possible side effect of Femara. I was also gaining approximately 2 pounds a month! I have been off of it for a month now, but am still having pain. It is worse in the mornings and evenings. Trying to grip with my hands is very difficult some mornings. My doctor said it could take a few months to get this out of my system.
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I have been on Femara for 3 months. After taking Tamoxifen for approximately 2 years, which I could not tolerate any longer, my oncologist put me on the Femara. While my hot flashes have pretty much disappeared, the joint and bone pain I am suffering is unbearable. My elbows, hands, fingers, knees, ankles and feet are the worse. In the mornings I cannot get out of bed. I take thyroid medicine in the morning and cannot open the bottle. It takes about 20 minutes before I can close my fingers or bend my toes. Nighttime is also bad. After sitting for short periods I cannot get up. I have never felt better in my life except for the constant agonizing pain. I am a very active 49 year old but feel like I am 90. This pain gets worse every day. I can only imagine what it will be like in 3 more months. I I am seeing my oncologist this week and am going to tell him I am stopping this drug. I believe the quality of my life is more important that the quantity.

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My doctor then put me on brand name Femara and the joint pain, head pain, and trigger finger all went away.

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Thanks for listening and giving me your experiences, ladies, I always know that I can come to this board and get support and advice from those who really know what it's like to battle this beast.

Ibuprofen does not help much, and yes at night seems to be a difficult time and after being on my feet for a long period of time.

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The duration of follow-up for both the main clinical study and the bone study were insufficient to assess fracture risk associated with long-term use of Femara.

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I've been taking Femara for 4 months and have stage 4 breast cancer.

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