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Can antidepressants stop working? However, in some people, a particular antidepressant may simply stop working over time. Doctors don't fully understand what causes the so-called "poop-out" effect or antidepressant tolerance — known as tachyphylaxis — or why it occurs in some people and not in others.
Does Cymbalta help with anxiety? Cymbalta works to bring balance back to the neurotransmitters called serotonin and norepinephrine. Both of these chemical messengers are connected to panic disorder. By bringing equilibrium back to the chemicals in your brain, Cymbalta can help alleviate anxiety, lessen panic attacks, and improve your mood.
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