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What is the best medication for dog allergies? Treating Dog Allergies Your doctor might recommend: Antihistamines, which block the effects of a chemical that triggers dog allergy symptoms; they're sold over the counter -- like cetirizine (Zyrtec), diphenhydramine (Benadryl), fexofenadine (Allegra), and loratadine (Claritin) -- or by prescription.
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