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Injection of BTA to the distal region of vastus lateralis muscle causes a short-term functional "denervation", which moderates the influence of vastus lateralis muscle on the knee extensor mechanism and increases the relative contribution of the vastus medialis muscle.
Goteborg, Sweden: Vastra Gotalandsregionen, Sahlgrenska Universitetssjukhuset, HTA-centrum; 2014.
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The median time to retreatment is 24 weeks, but should be no sooner than 12 weeks.
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On the other hand, there is insufficient evidence to draw a conclusion on the use of botulinum neurotoxin in the treatment of head and voice tremor.
Safety data, including increased post-void residual volume, defined as more than 200 ml irrespective of symptoms, was obtained at specified time points.
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Furthermore, an UpToDate review on “Overview of diplopia” (Bienfang, 2014) does not mention botulinum toxin as a therapeutic option.
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Mineral oil may be added to facilitate passage of stool without as much stretching or abrasion of the anal mucosa, but it is not recommended for indefinite use.
Your doctor will tell you which is right for you, and this will also be printed on the label of the pack to remind you.
Some ecchymosis may occur around the sphincterotomy site, but bleeding that requires therapy is extremely rare.
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Moreover, they stated that no study had yet determined the ideal dose of botulinum toxin type B for Frey's syndrome.
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The subpotent prescriptions ranged in potency from 34.
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Therefore, they concluded that there is no evidence of a benefit from botulinum toxin injection in the treatment of chronic tennis elbow.
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In a Cochrane review, Soares et al (2012) evaluated the effectiveness and safety of botulinum toxin in treating MPS, excluding MPS in neck and head muscles.
They assessed 23 full text articles for eligibility and all of these studies were excluded from the review.
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Two-year placebo-controlled trial of botulinum toxin A for leg spasticity in cerebral palsy.
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These investigators reported 3 cases of double vision related to extra-ocular muscle paresis after an injection of botulinum toxin for facial rejuvenation and blepharospasm.
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Upon re-injection, the degree and pattern of muscle spasticity may necessitate alterations in the dose of onabotulinumtoxinA and muscles to be injected.
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The suprapotent prescriptions ranged in potency from 117.
Symptoms may include confusion; difficulty breathing, especially when lying down; dizziness; drowsiness; fainting; lightheadedness, especially when standing; loss of consciousness; nausea; nervousness; slurred speech; unusual weakness; very slow heart rate.
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Botox is best known for its beneficial role in facial aesthetics but recent literature has highlighted its usage in multiple non-cosmetic medical and surgical conditions.
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CD or XR initial dose: 120 to 240 mg orally once a day.
The review reported that, in single trials, BTX- A was not associated with fewer migraine headaches per month versus valproate, topiramate, or amitriptyline.
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Monnier et al (2006) stated that musculoskeletal pain in patients with rheumatic disorders is among the emerging indications for botulinum toxin therapy.
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Ratings were completed at baseline (weeks 0 and 12), and 2 and 4 weeks post-injections.
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The BlueCross BlueShield Association Technology Evaluation Center reevaluated the use of botulinum toxin for primary headache disorders (BCBSA, 2004) and concluded that this does not meet the TEC criteria.
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Cordivari et al (2001) reported the findings of 14 patients with "dystonic clenched fist" (3 with cortico-basal ganglionic degeneration, 7 with Parkinson's disease, and 4 with dystonic-complex regional pain syndrome) who were treated with botulinum toxin A (BTXA, Dysport).
The maximum effect as an improvement of muscle tone was perceived within 4 weeks.
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