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Last year I spent some four months in Uganda on business. African countries are wonderful, full of fun and adventures, full of opportunities and surprises. For some poor people malaria becomes one - such surprises and adventures, if I can say so.by the time of my trip I had heard many scary stories about malaria and I was sure to take preventive measures to avoid falling ill with this terrible disease. I chose Mefloquine to be the medication I entrust my life and health as I have heard and read many positive reviews of the medication as the life saver. And I carefully observed my doctors instructions and took Mefloquine according to the prescription. In spite of the fact that many people told me Mefloquine was not good, I observed no side effects and never suffered from Malaria. I am sure that it is due to Mefloquine that I stayed healthy and sound as when in Uganda I visited many risky paces and have been bitten by insects for a lot of times. However I stayed protected from malaria and came back home with positive impressions only. I do recommend this medication to everyone travelling to Africa for pleasure or on business. And don't pay attention to bad comments, your life is more important than any side effects that you may not have just as well.
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After taking mefloquine I suffered from "sleep starts". Although I stopped using it, a new symptoms a rised like anxiety, parasthesia, hyper-reflexia, muscle twitching. It has been two years now but still having these symptoms but to a lesser extent.
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This medication is a nucleoside analog used in chemotherapy for treating certain types of cancer (like lung cancer, pancreatic cancer, breast cancer, ovarian cancer).
Giving this medicine to people who are travelling is absurd given the high rate of adverse effects!
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Between 1000 and 1500 cases are reported in the United States each year, virtually all being related to travel to endemic areas, and deaths being very rare and usually associated with misdiagnosis, inadequate therapy or lack of compliance.
Daily proguanil taken in conjunction with weekly chloroquine is an option for pregnant patients traveling to sub-Saharan Africa.
Low-dose quinine is effective in the treatment of chloroquine-resistant Plasmodium falciparum malaria in eastern Sudan.
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Mefloquine and artesunate combination therapy is the recommended first-line treatment for uncomplicated malaria throughout much of south-east Asia.
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Mefloquine hydrochloride tablets should not be prescribed for prophylaxis in patients with active depression, a recent history of depression, generalized anxiety disorder, psychosis, or schizophrenia or other major psychiatric disorders, or with a history of convulsions.
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In some patients these serious side effects can go on after Mefloquine is stopped.
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Higher genomic activity leads to the higher expression of proapoptotic genes, higher level of their protein products and elevated sensitivity to death ligand-induced apoptosis.
European Organisation of Military Associations found that several European armies are much more likely to prescribe alternative anti-malarials, like Malarone and doxycycline.
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Quinine exhibits considerable inter- and intraindividual variations in metabolism and elimination, with differences also seen in healthy compared with malaria-infected patients.
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People traveling to China to adopt children often worry about the health of the child but neglect their own health.
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Clinical trials of artemisinin and its derivatives in the treatment of malaria in China.
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According to the recent FDA data, generic drugs account for about 45-50 percent of all prescription drug purchases in the United States.
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