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Results observed with objective measurements, ie, in vitro assessments and electron microscopy, confirm the firming and restructuring effect clinically observed.

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Congenital hypoparathyroidism that occurs during the first few months of life may be temporary (transient) or permanent.

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One is inherited, but does not appear until adulthood, and the other develops as a result of long-term kidney damage.

That's important because researchers are beginning to find that low levels of vitamin D may be linked to other diseases, including breast and colon cancer, prostate cancer, high blood pressure, depression, and obesity.

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Clinical Review: The 2011 report on dietary reference intake for vitamin D: where do we go from here?

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Changes in BMD (expressed as percentage changes from baseline) between groups were compared using ANCOVA, adjusting for baseline BMD.

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Hypercalcemia should be documented on more than one occasion before a diagnostic workup is undertaken.

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We further sought to understand the mechanisms underlying these effects.

Voriconazole, a strong CYP3A4 inhibitor, may increase the serum concentration of calcitriol by decreasing its metabolism.

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The mean Allred score derived from the tumors in the calcitriol-treated group was lower than the control mice, whereas the dietary vitamin D group had the lowest score, indicating decreased ERα expression in the treated groups.

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En los pacientes con síndrome nefrótico y aquellos sometidos a hemodiálisis, es menor la predosis y los niveles picos de calcitriol.

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This may cause emergency conditions eg: coma in malignant hypercalcemia and tetany in hypocalcemia.

In addition to skeletal disorders, calcium and vitamin D deficits increase the risk of malignancies (in particular, of the colon, breast, and prostate gland), of chronic inflammatory and autoimmune disease (e.

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In a Cochrane review, these investigators evaluated the effects of vitamin D supplementation on the frequency of vitamin D deficiency, respiratory outcomes and vitamin D toxicity in the CF population.

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This occurs because of undersaturation of calcium hydroxyapatite in the extracellular fluid and the binding of calcium to non-collagenous proteins in the matrix ().

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Rocaltrol (calcitriol) is the most potent metabolite of vitamin D available.

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The use of acidsuppressant therapy histamine2receptor antagonists and proton pump inhibitors is recommended in pediatric patients with persistent symptoms of GERD.

In the kidneys, it affects calcium transport in the distal tubule by enhancing the action of parathyroid hormone and by inducing transient receptor potential cation channel, subfamily V, member 5 and calbindins.

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Note on documentation requirements: Laboratory tests results (before initiation of therapy) should be documented in the member's medical record showing the medical necessity of the treatment.

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