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Four-year results in the Combination of Avodart and Tamsulosin (CombAT) study revealed that for men with prostate volumes of 30-58 mL, combination therapy with dutasteride (dual 5-alpha-reductase inhibitor) and tamsulosin (alpha-1-blocker) improved symptoms, urinary flow, and QOL better than monotherapy with either drug, although not in men who had a prostate volume of 58 mL or more.

Patients with predominantly irritative symptoms of BPH are more likely to report that their QOL is affected than are men with predominantly obstructive symptoms.

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It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors.

The greatest efficacy for the alpha(1)-ARA and 5alphaRI combination was shown in patients with larger prostate size and more severe symptoms.

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Historically, anticholinergics were discouraged in men with BPH because of concerns of inducing urinary retention.

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Proscar Long-Term Efficacy and Safety Study Group Sustained decrease in incidence of acute urinary retention and surgery with finasteride for 6 years in men with benign prostatic hyperplasia.

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Combining a drug that slows prostate growth with one that relaxes bladder muscles may work better than the drugs given alone.

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The primary outcome was a decrease (improvement) in the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) of at least four points over 12 weeks of treatment.

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Hereditary or inflammatory causes may be involved.

There has been no signal of Torsade de Pointes in the extensive postmarketing experience with Alfuzosin outside the United States.

Because medical conditions such as high blood pressure or low blood sugar can affect blood flow, these conditions are frequently accompanied by dizziness.

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Most men will recover sperm production 3 to 12 months after they stop taking the drug.

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Treating symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate.

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Manufacturers, managed care organizations and regulatory agencies join efforts to reach each and every customer in the proper way in order to help you and improve your health

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Update on AUA Guideline on the Management of Benign Prostatic Hyperplasia.

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Although much valuable work has been published using fluorimetric assays to measure total catecholamine concentrations, the method is too non-specific and insensitive to accurately determine the very small quantities of epinephrine in plasma.

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Symptoms may include pain in the right or middle upper stomach area, fever, nausea and vomiting, or your skin or the white part of your eyes turning yellow.

Alfuzosin is mainly used for treating an enlarged prostate (benign prostatic hyperplasia, or BPH).

Improvement in patient survival or disease related symptoms has not been established.

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